TUSKEGEE, Ala. (AP) — Lucenia Dunn spent the early days of the coronavirus pandemic encouraging people to wear masks and keep a safe distance from each other in Tuskegee, a mostly Black city where the government once used unsuspecting African American men as guinea pigs in a study of a sexually transmitted disease.

Now, the onetime mayor of the town immortalized as the home of the infamous “Tuskegee syphilis study” is wary of getting inoculated against COVID-19. Among other things, she’s suspicious of the government promoting a vaccine that was developed in record time when it can’t seem to conduct adequate virus testing or consistently provide quality rural health care.

“I’m not doing this vaccine right now. That doesn’t mean I’m never going to do it. But I know enough to withhold getting it until we see all that is involved,” said Dunn, who is Black.

The coronavirus immunization campaign is off to a shaky start in Tuskegee and other parts of Macon County. Area leaders point to resistance among residents spurred by a distrust of government promises and decades of failed health programs. Many people in this city of 8,500 have relatives who were subjected to unethical government experimentation during the syphilis study.

“It does have an impact on decisions. Being in this community, growing up in this community, I would be very untruthful if I didn’t say that,” said Frank Lee, emergency management director in Macon County. Lee is Black.

Health experts have stressed both the vaccines’ safety and efficacy. They have noted that while the vaccines were developed with record-breaking speed, they were based on decades of prior research. Vaccines used in the U.S. have shown no signs of serious side effects in studies of tens of thousands of people. And with more than 26 million vaccinations administered in the U.S. alone so far, no red flags have been reported.

Tuskegee is not a complete outlier. A recent survey conducted by the communications firm Edelman revealed that as of November, only 59% of people in the U.S. were willing to get vaccinated within a year with just 33% happy to do so as soon as possible.

But skepticism seems to run deeper here.

When Alabama and the rest of the South were still segregated by race, government medical workers starting in 1932 withheld treatment for unsuspecting men infected with syphilis in Tuskegee and surrounding Macon County so physicians could track the disease. The study, which involved about 600 men, ended in 1972 only after it was revealed by The Associated Press.

A lawsuit filed on behalf of the men by Black Tuskegee attorney Fred Gray resulted in a $9 million settlement, and then-President Bill Clinton formally apologized on behalf of the U.S. government in 1997. But the damage left a legacy of distrust that extends far beyond Tuskegee: A December survey showed 40% of Black people nationwide said they wouldn’t get the coronavirus vaccine. Such hesitancy is more entrenched than among white people, even though Black Americans have been hit disproportionately hard by the virus.

Nurse Marianne Williams administers a COVID-19 vaccine to a woman as a coworker looks on at the county health department in Tuskegee, Ala., Monday, Jan. 25, 2021. The clinic has yet to reach its maximum capacity for immunizing people in the mostly Black city, the site of the infamous “Tuskegee syphilis study,” that ended in 1972. (AP Photo/Jay Reeves)

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